Genetic variants reveal new targets for chronic kidney disease treatment

The kidney does more than double or even triple duty compared to other organs—it extracts waste, balances body fluids, forms urine, regulates blood pressure, and secretes hormones. Given this complexity, when things go wrong, havoc can ensue, causing a suite […]

Genetic mutation may increase risk of pancreatic cancer in females

LONDON, ON – In a new study from Lawson Health Research Institute and Western University’s Schulich School of Medicine & Dentistry, researchers have found that mutation of a gene called ATRX may lead to increased risk of developing pancreatitis and […]

The genomic crash: researchers could reclassify over 4000 genes as non

A new study suggests that 20% of the previously accepted human genome has been misinterpreted and actually consists of non-coding DNA. Recent research led by Michael Tress of the Spanish National Cancer Research Centre (Madrid, Spain), has discovered that up […]

Genomic study brings us closer to precision medicine for type 2 diabetes

Most patients diagnosed with type 2 diabetes are treated with a “one-size-fits-all” protocol that is not tailored to each person’s physiology and may leave many cases inadequately managed. A new study by scientists at the Broad Institute of MIT and […]

Researchers identify new genetic disorder

Researchers from Michigan State University College of Human Medicine and physicians from Spectrum Health have identified for the first time in a human patient a genetic disorder only previously described in animal models. Credit: CC0 Public Domain The disorder is […]

Can we teach heart cells to grow up?

A master genetic regulator cardiomyocytes that need to mature may be a clue toward getting heart muscle to regenerate BOSTON CHILDREN’S HOSPITAL Scientists around the world have been trying to replace damaged heart tissue using lab-made heart-muscle cells (cardiomyocytes), either injecting them into the heart or applying patches laced […]

Clinical gene discovery program solves 30 medical mysteries

Brigham Genomic Medicine brings together scientists and clinicians to diagnose, discover genetic underpinnings of disease and shape treatment BRIGHAM AND WOMEN’S HOSPITAL Boston, MA (September 17, 2018) A table in a recently published paper tells the story of 30 families […]

Study of one million people leads to world’s biggest advance in blood pressure genetics

Over 500 new gene regions that influence people’s blood pressure have been discovered in the largest global genetic study of blood pressure to date, led by Queen Mary University of London and Imperial College London. Involving more than one million […]

Researchers find answers as to why some people are at risk of gout

University of Otago researchers has helped characterize a genetic variant that enables new understanding of why some people are at risk of gout, a painful and debilitating arthritic disease. Image: Gout in X-ray of left foot. Credit: Hellerhoff/Wikipedia. Gout is caused by […]