Researchers find answers as to why some people are at risk of gout

University of Otago researchers has helped characterize a genetic variant that enables new understanding of why some people are at risk of gout, a painful and debilitating arthritic disease. Image: Gout in X-ray of left foot. Credit: Hellerhoff/Wikipedia. Gout is caused by […]

Study cracks open the secrets of the cancer-causing BRCA1 gene

Lawsuits didn’t do it, public shaming didn’t do it, patients and doctors banding together to “free the data” couldn’t do it: For 22 years Myriad Genetics, one of the oldest genetic testing companies, has refused to make public its proprietary database of […]

One in five human genes are not ‘real’

New research could change the face of biomedicine; the human genome is found to contain far fewer “real,” or protein-encoding, genes than it was previously believed. Our DNA may contain far fewer ‘real’ genes than we initially thought. In the early 1990s, […]

Breakthrough in muscular dystrophy research after scientists edit DNA to rebuild muscles Breakthrough in muscular dystrophy research after scientists edit DNA to

Duchenne muscular dystrophy affects as many as one in every 3,500 boys It kills patients by their mid-30s by weakening the heart and breathing muscles Scientists have managed to edit DNA to strengthen weakened muscles Levels of a vital muscle […]

Genome-wide study identifies genes linked to diverticular disease

More than half of adults in the Western hemisphere over the age of 40 have small bulging pouches inside their intestine known as diverticula. Caused by a weakening of the outer lining of the intestine, these pouches are typically harmless. […]

New mechanism activates bone-building cells in Osteoperosis

The number of osteoporosis medications that promote bone formation is few compared to those that suppress bone resorption. A research group led by Kumamoto University scientists has discovered that the gene SIRT7 is important for bone formation, and has discovered a […]

Researchers can forecast risk of deadly vascular condition from genome sequence

A new approach that distills deluges of genetic data and patient health records has identified a set of telltale patterns that can predict a person’s risk for a common, and often fatal, cardiovascular disease, according to a new study from […]

Stray proteins cause genetic disorders

The seizures typically begin in the first months of life. It often takes years, however, before those suffering from the rare glucose transporter type 1 (Glut1) deficiency syndrome obtain a correct diagnosis. If the disorder goes untreated, affected children experience […]

Mutations, drugs drive cancer by blurring growth signals

Novel technique lets researchers control common cancer pathway in the lab with pulses of light, revealing the hidden importance of precise timing in cellular signaling UNIVERSITY OF CALIFORNIA – SAN FRANCISCO Genetic mutations in a form of non-small cell lung cancer (NSCLC) […]