Mononuclear phagocytes can both promote and inhibit inflammation

Mononuclear phagocytes can both promote and inhibit inflammation. A Team from Ludwig-Maximilians-Universitaet (LMU) in Munich has now shown that individual phagocytes in the central nervous system can play both roles, sequentially adopting different phenotypes with distinct functions. Mononuclear phagocytes, which […]

Biochemists described a new mechanism for autoimmunity suppression

RUDN biochemists suggested a new mechanism by which the human body prevents the development of autoimmune diseases, allergies, and implant rejection. They report that regulatory T-cells are able to suppress the reproduction of autoimmune cells. The work was published in Molecular […]

Researchers testing new brain cancer vaccine

Rush University Medical Center is part of a new clinical trial testing whether an experimental vaccine can help patients’ immune systems stop the spread of glioblastoma—an aggressive form of brain cancer with very few current treatment options. Glioblastoma (histology slide). […]

Enhancing immune checkpoint inhibitor therapy using treatment combination

A combination of a novel inhibitor of the protein CK2 (Casein kinase 2) and an immune checkpoint inhibitor has dramatically greater antitumor activity than either inhibitor alone, according to research from The Wistar Institute that was published online in Cancer […]

Immunotherapy could offer hope for some men with aggressive prostate cancers

A group of men with especially aggressive prostate cancer may respond unusually well to immunotherapy, a major new study reports. Micrograph showing prostatic acinar adenocarcinoma (the most common form of prostate cancer) Credit: Wikipedia The research offers the possibility of […]

A ‘homing system’ targets therapeutic T-cells to brain cancer

A multi-institution international team led by researchers at Baylor College of Medicine has developed a new strategy to overcome one of the main obstacles to the treatment of brain cancer—access to the tumor. Under the influence of cancer, the blood-brain […]

Killer cell Immunotherapy offers potential cure for advanced pancreatic cancer

A new approach to treating pancreatic cancer using ‘educated killer cells’ has shown promise, according to a new study by UNSW medical researchers. Researchers from UNSW Sydney and the California Institute of Biomedical Research (CALIBR) have demonstrated the success of […]

Single-dose drug can shorten flu symptoms by about a day, studies suggest

No significant side effects noted in pair of clinical trials in U.S., Japan UNIVERSITY OF VIRGINIA HEALTH SYSTEM IMAGE: FREDERICK HAYDEN, MD, IS A RESEARCHER AT THE UNIVERSITY OF VIRGINIA SCHOOL OF MEDICINE. A single dose of a new influenza drug […]